Developing a new coating for drug-eluting stents
Official title: Porous Inorganic Framework Thin Film as Drug-Eluting Stent Coating
Funded at California State University Long Beach · NIH-10701711 · Data updated 2026-11-12
This study is looking at new coatings for stents, which are used to keep your blood vessels open after treatment, to see how changes in their structure can help them deliver medicine better and make stents safer and more effective for people with blocked arteries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State University Long Beach NIH-funded |
| Lab location | 1 site (Long Beach, United States) |
| Project start | September 11, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $110,625 |
| NIH project number | 5SC3GM136590-04 |
| Project ID | NIH-10701711 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing procedures like percutaneous transluminal angioplasty who may benefit from improved stent technology.
✕Less likely to help
Patients who have already had successful stent placements or those not requiring angioplasty may not benefit from this research.
What this research studies
This research focuses on creating porous inorganic framework thin films that can be used as coatings for drug-eluting stents, which are devices used to keep blood vessels open after angioplasty. The researchers aim to understand how the chemical and structural properties of these coatings affect their ability to load and release drugs effectively. By modifying these thin films and testing their performance in the lab, the team hopes to improve drug delivery directly to the site of vascular interventions. The ultimate goal is to enhance the effectiveness and safety of stents used in treating blocked arteries.
Why it matters
Potential benefit: If successful, this research could lead to more effective drug-eluting stents that reduce the risk of restenosis and improve patient outcomes after angioplasty procedures.
How similar studies have gone: Other research has shown promise in using innovative materials for drug delivery in stents, indicating that this approach could lead to significant advancements.
Where this research is happening
-
California State University Long Beach
Long Beach, United States Active
Researchers
- Principal investigator: Tian, Fangyuan — California State University Long Beach
- Study coordinator: Tian, Fangyuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.