Developing a new brain imaging system for better understanding of brain chemistry

NeuroExplorer: Ultra-high Performance Human Brain PET Imager for Highly-resolved In Vivo Imaging of Neurochemistry

NIH-funded research Yale University · NIH-10927311

This study is working on a new brain imaging system that will help doctors see your brain more clearly and understand how it works, which could lead to better diagnoses and treatment options for you.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10927311 on NIH RePORTER

What this research studies

This research focuses on creating an advanced Positron Emission Tomography (PET) system specifically designed for brain imaging. The NeuroEXPLORER system aims to enhance the sensitivity and resolution of brain scans, allowing for a more detailed understanding of brain physiology, neurotransmitter dynamics, and receptor pharmacology. By utilizing novel radiotracers and advanced technology, the research team will build and test this new imaging system over the next few years. Patients may benefit from improved diagnostic capabilities and treatment monitoring through more accurate brain imaging.

Who could benefit from this research

Good fit: Ideal candidates for participation include children and adolescents up to 21 years old who may be experiencing neurological disorders.

Not a fit: Patients with conditions unrelated to brain chemistry or those outside the age range of 0-21 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise brain imaging techniques that improve diagnosis and treatment of neurological conditions.

How similar studies have performed: Previous advancements in brain imaging technologies have shown significant success, indicating a strong potential for this novel approach.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.