Developing a new antiviral treatment for COVID-19

IND-Enabling Development of a Small Molecule COVID Therapeutic

NIH-funded research Oyagen, INC. · NIH-10813199

This study is testing a new antiviral drug called sangivamycin to see how well it works against COVID-19 in hamsters, with hopes that it could eventually help people fighting the virus.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionOyagen, INC. NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10813199 on NIH RePORTER

What this research studies

This research focuses on the development of sangivamycin, an antiviral compound, to treat COVID-19. The project will assess how the drug works in the body and its effectiveness against the virus in animal models, specifically Golden Syrian hamsters. The goal is to gather the necessary data to support an application for clinical trials in humans, which could lead to new treatment options for COVID-19 patients. The research builds on previous findings that showed sangivamycin's potential against various COVID-19 variants.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals who are at risk of severe COVID-19 infection or those who have tested positive for the virus.

Not a fit: Patients who are not infected with COVID-19 or those who have already recovered from the virus may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new therapeutic option for patients suffering from COVID-19.

How similar studies have performed: Previous research has shown promise with similar antiviral compounds, but this specific approach with sangivamycin is novel and untested in the context of COVID-19.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.