Developing a monkey version of a cognitive test for early signs of Alzheimer's disease
Creation of a monkey mini mental state exam (mMMSE) for identifying early cognitive deficits related to Alzheimer’s disease and related dementias
This study is working on a quick test for monkeys to help spot early signs of memory problems like those seen in Alzheimer's, which could help us understand how aging affects thinking and find better ways to help people sooner.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10683330 on NIH RePORTER |
What this research studies
This research aims to create a monkey mini mental state exam (mMMSE) to identify early cognitive deficits related to Alzheimer's disease and related dementias. By using nonhuman primate models, the study seeks to understand the biological mechanisms of aging and vulnerability to cognitive decline. The mMMSE will serve as a quick screening tool, inspired by existing human cognitive assessments, to facilitate early intervention strategies. This approach allows for the exploration of genetic factors and variations in aging outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients who are not at risk for Alzheimer's disease or do not exhibit any cognitive deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and intervention strategies for Alzheimer's disease, potentially improving patient outcomes.
How similar studies have performed: Previous research has successfully utilized similar cognitive screening tools in humans, suggesting potential for success in this novel approach with nonhuman primates.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Bliss-Moreau, Eliza — University of California at Davis
- Study coordinator: Bliss-Moreau, Eliza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.