Developing a model to diagnose and monitor dementia in Parkinson's disease using imaging and other measures
Towards Generating a Multimodal and Multivariate Classification Model from Imaging and Non-Imaging Measures for Accurate Diagnosis and Monitoring of Dementia in Parkinsons disease
This study is looking for the best ways to spot dementia in people with Parkinson's disease by using special brain scans and other health information, so we can help diagnose it earlier and find better treatments for those who need them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10889167 on NIH RePORTER |
What this research studies
This research aims to identify the most effective biomarkers for diagnosing dementia in patients with Parkinson's disease by utilizing a combination of advanced imaging techniques and non-imaging data. The study will analyze neuroimaging measures such as diffusion-weighted MRI and resting-state functional MRI alongside demographic, clinical, genetic, and cerebrospinal fluid measures. By understanding the underlying mechanisms of dementia in Parkinson's disease, the research seeks to improve early diagnosis and patient management. This could lead to better prognostic tools and the identification of patients who may benefit from new treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are at risk of developing dementia.
Not a fit: Patients who do not have Parkinson's disease or those who are not at risk of developing dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and earlier diagnoses of dementia in Parkinson's disease, improving patient outcomes and treatment options.
How similar studies have performed: Previous research has shown promise in using multimodal approaches to identify biomarkers for dementia, suggesting that this method could be effective.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Mishra, Virendra R — University of Alabama at Birmingham
- Study coordinator: Mishra, Virendra R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.