Developing a method to sample fluids from the testes to improve drug delivery.
Development/Validation of Rete Testis Microcannulation for the Assessment of Novel Chemical Scaffolds That Penetrate the Blood Testis Barrier
['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-10932396
This study is exploring a new way to collect fluids from a part of the male reproductive system that’s hard to reach, which could help improve treatments for male contraception and other health issues like viral diseases and cancers.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10932396 on ClinicalTrials.gov |
What this research studies
This research focuses on creating and validating a technique to sample fluids from the rete testis, which is located behind the blood-testis barrier. This barrier makes it difficult for drugs to reach developing sperm cells, which is crucial for developing male contraceptives and fertility treatments. By overcoming this barrier, the research aims to enhance the effectiveness of drugs targeting various health issues, including viral diseases and cancers. The approach involves innovative methods to analyze these fluids, potentially leading to significant advancements in drug discovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are males who may benefit from improved contraceptive options or treatments for conditions affecting fertility or testicular health.
Not a fit: Patients who are not male or those who do not have conditions related to fertility or the testes may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective male contraceptives and treatments for various diseases by improving drug delivery to the testes.
How similar studies have performed: While this approach is innovative, similar research has shown promise in overcoming biological barriers for drug delivery in other contexts.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WONG, HENRY L — UNIVERSITY OF MINNESOTA
- Study coordinator: WONG, HENRY L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, Cancers