Developing a low power device for monitoring and controlling seizures
Official title: A flexible, low power, multi-channel, real-time BCI for seizure monitoring and Modulation
Funded at Yale University · NIH-11046553 · Data updated 2026-11-12
This study is working on a special device that can be placed in the brain to help control seizures in people with epilepsy by monitoring and adjusting brain activity in real-time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $563,877 |
| NIH project number | 5R01NS136442-02 |
| Project ID | NIH-11046553 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with medically refractory epilepsy, particularly those with focal seizure disorders.
✕Less likely to help
Patients whose seizures are well-controlled with existing treatments may not benefit from this research.
What this research studies
This research focuses on creating an implantable device that can monitor and modulate brain activity to control seizures in patients with epilepsy. The device aims to overcome limitations of current technologies by using a programmable, low power design that can operate in real-time across multiple brain regions. The approach involves advanced signal processing and will be tested through both bench and animal studies to ensure its effectiveness before potential human application.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option for patients with epilepsy who do not respond to traditional medications.
How similar studies have gone: Previous research has shown promise in using neuromodulation devices for seizure control, indicating potential for success with this novel approach.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Manohar, Rajit — Yale University
- Study coordinator: Manohar, Rajit
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.