Developing a low-cost test for detecting HIV-1 RNA levels
Self-Powered Sample Concentrating and CRISPR-based Biosensing for Moile HIV-1 RNA Detection
['FUNDING_OTHER'] · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · NIH-10899624
This study is working on a quick and easy way to test for HIV that can give results in under 35 minutes, helping people get diagnosed early and monitor their treatment, all without needing to go to a lab.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT (nih funded) |
| Locations | 1 site (FARMINGTON, UNITED STATES) |
| Trial ID | NIH-10899624 on ClinicalTrials.gov |
What this research studies
This research focuses on creating an affordable and rapid testing method for detecting HIV-1 RNA levels in patients. By utilizing a self-powered sample concentrating system combined with CRISPR-based biosensing technology, the goal is to provide a point-of-care diagnostic tool that can deliver results in under 35 minutes. This innovative approach aims to improve early diagnosis of acute HIV infections and monitor treatment effectiveness for those already receiving antiretroviral therapy. The method is designed to be simple enough for use outside of traditional laboratory settings, making it accessible to a wider population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of HIV infection or those undergoing antiretroviral treatment who require regular monitoring of their viral load.
Not a fit: Patients who are not at risk for HIV or those who are not undergoing treatment for HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a significant improvement in early HIV detection and monitoring, ultimately enhancing patient outcomes.
How similar studies have performed: Other research has shown promise in developing rapid diagnostic tools for HIV, but this specific approach using CRISPR technology is relatively novel.
Where this research is happening
FARMINGTON, UNITED STATES
- UNIVERSITY OF CONNECTICUT SCH OF MED/DNT — FARMINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, CHANGCHUN — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
- Study coordinator: LIU, CHANGCHUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus