Developing a flexible system to improve heart tissue engineering
Official title: Flexible bioelectronics platform converging capillary-like delivery network and sensing feedback network for improving cardiac tissue engineering
Funded at University of Massachusetts Amherst · NIH-10990630 · Data updated 2026-11-12
This study is working on a new technology that helps grow heart tissues more effectively by mimicking how blood vessels work, which could lead to better treatments for heart disease in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Amherst NIH-funded |
| Lab location | 1 site (Hadley, United States) |
| Project start | September 6, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $488,026 |
| NIH project number | 1R33HL175683-01 |
| Project ID | NIH-10990630 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cardiac diseases or conditions that could benefit from advanced tissue engineering solutions.
✕Less likely to help
Patients with non-cardiac related health issues or those who do not require tissue engineering interventions may not benefit from this research.
What this research studies
This research focuses on creating a flexible bioelectronic platform that mimics the natural capillary network of the heart to enhance the development of cardiac tissues. By integrating a delivery network for oxygen and nutrients with a sensing network for real-time feedback, the project aims to improve the maturation and functionality of heart tissues derived from stem cells. Patients may benefit from advancements in heart disease modeling and potential future treatments through improved tissue engineering techniques.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for heart diseases by improving the development of cardiac tissues for transplantation and disease modeling.
How similar studies have gone: Other research has shown promise in using bioelectronic systems for tissue engineering, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
-
University of Massachusetts Amherst
Hadley, United States Active
Researchers
- Principal investigator: Yao, Jun — University of Massachusetts Amherst
- Study coordinator: Yao, Jun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.