Developing a faster method to analyze proteins in cancer patients
Official title: A Real-Time AI-Driven High-Throughput Proteomics Data Acquisition Method for Clinical Applications
Funded at Massachusetts General Hospital · NIH-11032878 · Data updated 2026-11-12
This study is testing a new way to quickly and effectively analyze proteins in cancer patients' blood and tissue samples, which could help doctors understand cancer better and provide more accurate information for diagnosis and treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | February 12, 2024 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $234,218 |
| NIH project number | 5R61CA287026-02 |
| Project ID | NIH-11032878 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with cancer who are undergoing treatment or evaluation.
✕Less likely to help
Patients with non-cancerous conditions or those who are not undergoing any diagnostic evaluations may not benefit from this research.
What this research studies
This research focuses on creating a new method for analyzing proteins in cancer patients using advanced mass spectrometry techniques. By increasing the speed and efficiency of protein analysis, the goal is to better understand the complexities of cancer at a molecular level. This method aims to significantly enhance the number of proteins that can be analyzed from blood and tissue samples, potentially leading to improved diagnostics and treatment strategies. Patients may benefit from more accurate and timely information about their cancer through this innovative approach.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate cancer diagnostics, improving treatment outcomes for patients.
How similar studies have gone: Other research has shown promise in using advanced mass spectrometry techniques for proteomics, indicating that this approach could be effective.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Haas, Wilhelm — Massachusetts General Hospital
- Study coordinator: Haas, Wilhelm
Related research
Other NIH-funded projects on the same topics.
-
Global TravEpiNet: Pregnant Travelers Health and Disease Prevention Network
This grant supports a national network to improve health and prevent infections among international travelers, with a special focus on pregnant travelers.
-
Soluble ST2 and the course of lung injury in ARDS
A doctor-scientist at a top hospital is studying how a molecule called soluble ST2 may influence how lung injury starts and heals in patients with ARDS and related conditions.
-
Role of airway macrophages in lung health and allergic disease
A doctor-scientist at a major hospital wants to study how immune cells in the airways develop and influence asthma and other airway diseases.
-
Global TravEpiNet: Understanding and Protecting US Travelers, including Pregnant Travelers
A large U.S. network studies international travelers, including pregnant travelers, to understand illness risks and reduce the spread of infections.
-
Gait speed from wearable sensors to guide ALS trials
A patient-friendly look at using wearable sensors to measure how fast people with ALS walk, to help run better ALS trials.
-
Determinants of Post-Stroke Cognitive Outcomes and Vascular Effects on Recovery
A large, multi-site effort aims to understand why some stroke survivors develop long-term cognitive problems and dementia, and how vascular health and pre-existing brain changes influence recovery.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.