Developing a device to restore vision for blind individuals
Functional analysis of an LGN-based visual prosthesis
['FUNDING_OTHER'] · VA BOSTON HEALTH CARE SYSTEM · NIH-10867260
This study is testing a new device that could help restore vision for people who are blind, especially those with conditions like age-related macular degeneration and diabetic retinopathy, by placing it in a part of the brain that might give them better sight.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VA BOSTON HEALTH CARE SYSTEM (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10867260 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a visual prosthesis that aims to restore vision in individuals who are blind, particularly those affected by conditions like age-related macular degeneration and diabetic retinopathy. The approach involves implanting a device in the lateral geniculate nucleus (LGN) of the thalamus, which is less affected by common causes of blindness, allowing for potentially higher visual acuity. The study seeks to address the significant impact of blindness on quality of life, including increased risks of depression and accidental falls. By targeting a different area of the brain, this research hopes to provide a viable treatment option for a broader range of blind patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals over the age of 45 who are blind due to conditions like glaucoma, age-related macular degeneration, or diabetic retinopathy.
Not a fit: Patients who are not blind or have conditions that do not affect the visual pathways may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for blind individuals by restoring their vision.
How similar studies have performed: While there have been various approaches to restoring vision, this specific method targeting the LGN is relatively novel and has not been extensively tested in prior studies.
Where this research is happening
BOSTON, UNITED STATES
- VA BOSTON HEALTH CARE SYSTEM — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FRIED, SHELLEY — VA BOSTON HEALTH CARE SYSTEM
- Study coordinator: FRIED, SHELLEY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.