Developing a device to monitor and influence brain activity in young mice
Organic Closed-loop Electrochemical Array for Neurodevelopment (OCEAN)
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-11130849
This study is working on a special device that can both listen to brain signals and release helpful chemicals in young mice to learn how their brains develop, which could help us understand brain functions and mental health issues better in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-11130849 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a fully implantable device that can both detect brain signals and deliver neurochemicals in developing mouse pups. By using advanced materials like conducting polymers and ionic circuits, the project aims to understand how brain activity and neurochemistry interact during critical periods of brain maturation. The goal is to gain insights into cognitive functions and neuropsychiatric disorders by monitoring these processes in real-time as the mice grow. This innovative approach could provide valuable data on the development of brain circuits and their implications for future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research would be young mice, particularly mouse pups in the early stages of brain development.
Not a fit: Patients who are not involved in animal studies or those outside the scope of neurodevelopmental research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating neurodevelopmental disorders.
How similar studies have performed: While the approach is innovative, similar technologies have shown promise in other areas of neurophysiology, suggesting potential for success.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KHODAGHOLY, DION — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: KHODAGHOLY, DION
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.