Developing a comprehensive testing system for Alzheimer's disease in marmosets
Multimodal Disease Characterization Core
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10899738
This study is looking at how certain signs of Alzheimer's disease develop in marmosets over time, using advanced imaging and behavior tests, to help us better understand healthy aging and when Alzheimer's might start.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10899738 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a standardized testing pipeline to assess various biomarkers related to Alzheimer's disease in marmosets. It aims to evaluate functional, behavioral, and clinical indicators over time to understand healthy aging and the onset of Alzheimer's. The study will utilize advanced neuroimaging techniques, behavioral assessments, and biomarker analysis to track changes from birth until disease onset. By establishing best practices and protocols, the research seeks to enhance our understanding of Alzheimer's disease progression.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals at risk for Alzheimer's disease, particularly those with early-onset or late-onset familial histories.
Not a fit: Patients with non-Alzheimer's related dementias or cognitive impairments may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for early detection and intervention in Alzheimer's disease.
How similar studies have performed: Previous research has shown success in using multimodal approaches for understanding Alzheimer's disease, indicating that this methodology is promising.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SILVA, AFONSO C — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: SILVA, AFONSO C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease model