Developing a comprehensive approach to understand and treat Alzheimer's disease and related dementias.
A Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer’s Disease and Longevity
This study is working to combine different types of health information to better understand Alzheimer's and related dementias, with the hope of finding new treatments that can help slow down the disease and improve the lives of patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11115357 on NIH RePORTER |
What this research studies
This research aims to create a sophisticated infrastructure that integrates various biological data types, including genetic and real-world patient information, to better understand Alzheimer's disease (AD) and related dementias (ADRD). By utilizing a multimodal approach, the project seeks to identify key biological factors and mechanisms that contribute to these conditions. The goal is to develop targeted therapies that can modify the disease's progression and improve patient outcomes. Patients may benefit from advancements in treatment options that are informed by a deeper understanding of the underlying biology of aging and dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias, particularly those who are experiencing early to moderate stages of the disease.
Not a fit: Patients with advanced Alzheimer's disease or those with other unrelated cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, effective treatments for Alzheimer's disease and related dementias, improving the quality of life for patients.
How similar studies have performed: Previous research utilizing multimodal and systems biology approaches has shown promise in understanding complex diseases, suggesting that this innovative method could yield significant insights and advancements.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Cheng, Feixiong — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Cheng, Feixiong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.