Developing a compact, cryogen-free magnet for advanced NMR spectroscopy
A Benchtop Cryogen-Free 23.5-T/25-mm-RT-Bore Magnet for 1-GHz microcoil NMR Spectroscopy
['FUNDING_R01'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-10903935
This study is working on a new type of smaller and more affordable magnet that helps scientists study tiny molecules like proteins using a special technique called NMR spectroscopy, making it easier for more labs to do important research in areas like biochemistry and medicine.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-10903935 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a benchtop, cryogen-free magnet that operates at 23.5 Tesla for 1-GHz microcoil nuclear magnetic resonance (NMR) spectroscopy. By utilizing high-temperature superconducting materials, the project aims to provide a more accessible and cost-effective alternative to existing NMR magnets, which are typically large and expensive. The new design will allow for better resolution and sensitivity in analyzing complex molecules, such as proteins, which could enhance research in various fields including biochemistry and pharmaceuticals. The project builds on previous successful prototypes and aims to make high-field NMR spectroscopy available to more laboratories.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include researchers and scientists in biochemistry and related fields who require advanced analytical techniques for molecular analysis.
Not a fit: Patients who are not involved in research or do not work in fields requiring NMR spectroscopy may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the cost and increase the accessibility of advanced NMR spectroscopy for studying complex biological molecules.
How similar studies have performed: Previous research has shown success with high-temperature superconducting magnets, indicating that this approach has potential for significant advancements in NMR technology.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARK, DONGKEUN — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: PARK, DONGKEUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.