Developing a blood test to improve early detection of breast cancer.
Official title: Admin Core
Funded at Fred Hutchinson Cancer Center · NIH-11123887 · Data updated 2026-11-12
This study is working on a new blood test to help find breast cancer earlier, especially for women with dense breast tissue, so that doctors can catch more cases that mammograms might miss.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | June 5, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $432,004 |
| NIH project number | 5U2CCA271873-03 |
| Project ID | NIH-11123887 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women at high risk for breast cancer, particularly those with dense breast tissue.
✕Less likely to help
Patients who have already been diagnosed with advanced breast cancer may not benefit from this research.
What this research studies
This research aims to create a blood-based test that complements mammography for the early detection of breast cancer. Current mammography methods can miss about one in seven breast cancers, particularly in women with dense breast tissue. By utilizing advanced biomarker discovery techniques and patient-derived xenograft models, the study will identify and validate specific protein biomarkers in blood samples. The goal is to enhance the sensitivity and specificity of breast cancer detection, potentially leading to earlier diagnosis and better outcomes for patients.
Why it matters
Potential benefit: If successful, this research could lead to a more accurate and reliable method for early breast cancer detection, improving survival rates.
How similar studies have gone: Other research has shown promise in using blood tests for cancer detection, indicating that this approach could be effective.
Where this research is happening
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Fred Hutchinson Cancer Center
Seattle, United States Active
Researchers
- Principal investigator: Paulovich, Amanda G — Fred Hutchinson Cancer Center
- Study coordinator: Paulovich, Amanda G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.