Developing a blood test to identify aggressive prostate cancer types
Official title: Clinical Translation of a Large Oncosome-Based Prostate Cancer Blood Test
Funded at Cedars-Sinai Medical Center · NIH-10990336 · Data updated 2026-11-12
This study is working on a simple blood test that can help find different types of aggressive prostate cancer and see how well treatments are working for patients, making it easier for doctors to tailor care to individual needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $649,486 |
| NIH project number | 1R01CA287075-01A1 |
| Project ID | NIH-10990336 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with lethal, metastatic prostate cancer, particularly those with biologically aggressive disease.
✕Less likely to help
Patients with non-aggressive or early-stage prostate cancer may not benefit from this research.
What this research studies
This research aims to create a minimally invasive blood test that can detect different molecular subtypes of aggressive prostate cancer. By analyzing large oncosomes found in the blood of patients, the study seeks to identify biomarkers that indicate how well patients respond to treatments. The approach involves advanced technologies and extensive testing on a large cohort of prostate cancer specimens to ensure the test's clinical utility. Patients will be monitored over time to assess changes in their tumor characteristics and treatment responses.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized treatment strategies for patients with aggressive prostate cancer.
How similar studies have gone: Other research has shown promise in using liquid biopsies for cancer detection, indicating that this approach could be effective.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Di Vizio, Dolores — Cedars-Sinai Medical Center
- Study coordinator: Di Vizio, Dolores
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.