Developing a blood test to identify aggressive prostate cancer types
Clinical Translation of a Large Oncosome-Based Prostate Cancer Blood Test
['FUNDING_R01'] · CEDARS-SINAI MEDICAL CENTER · NIH-10990336
This study is working on a simple blood test that can help find different types of aggressive prostate cancer and see how well treatments are working for patients, making it easier for doctors to tailor care to individual needs.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CEDARS-SINAI MEDICAL CENTER (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10990336 on ClinicalTrials.gov |
What this research studies
This research aims to create a minimally invasive blood test that can detect different molecular subtypes of aggressive prostate cancer. By analyzing large oncosomes found in the blood of patients, the study seeks to identify biomarkers that indicate how well patients respond to treatments. The approach involves advanced technologies and extensive testing on a large cohort of prostate cancer specimens to ensure the test's clinical utility. Patients will be monitored over time to assess changes in their tumor characteristics and treatment responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with lethal, metastatic prostate cancer, particularly those with biologically aggressive disease.
Not a fit: Patients with non-aggressive or early-stage prostate cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized treatment strategies for patients with aggressive prostate cancer.
How similar studies have performed: Other research has shown promise in using liquid biopsies for cancer detection, indicating that this approach could be effective.
Where this research is happening
LOS ANGELES, UNITED STATES
- CEDARS-SINAI MEDICAL CENTER — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DI VIZIO, DOLORES — CEDARS-SINAI MEDICAL CENTER
- Study coordinator: DI VIZIO, DOLORES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.