Detecting pancreatic cancer earlier using small amounts of cyst fluid

Using microvolumetric cyst fluid proteolysis for early detection of pancreatic cancer

['FUNDING_U01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11092151

This study is looking at a new way to spot pancreatic cancer early by examining small amounts of fluid from cysts in the pancreas, which could help avoid unnecessary surgeries and lead to better outcomes for patients.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11092151 on ClinicalTrials.gov

What this research studies

This research focuses on improving the early detection of pancreatic cancer by analyzing cystic lesions in the pancreas. It utilizes a novel method that requires only a tiny volume of cyst fluid to identify potentially cancerous changes, which is a significant improvement over current diagnostic techniques that often need larger samples. By refining the identification of mucinous pancreatic cysts, the research aims to reduce unnecessary surgeries and improve patient outcomes. The study will validate its findings using samples from a well-established biorepository.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic cystic lesions, particularly those with indeterminate cysts.

Not a fit: Patients without pancreatic cystic lesions or those with cysts that are already confirmed as non-mucinous may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and less invasive diagnostic methods for pancreatic cancer, potentially saving lives.

How similar studies have performed: Previous research has shown promise in using proteomic approaches for cancer detection, indicating that this method could be a significant advancement in the field.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.