Detecting multiple brain metabolites using advanced magnetic resonance techniques
Multi-voxel spectral editing at 3T
This study is working on new ways to use brain scans to better detect important chemicals in the brain, which could help doctors diagnose and monitor neurological conditions more effectively.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10741756 on NIH RePORTER |
What this research studies
This research focuses on improving magnetic resonance spectroscopy (MRS) to non-invasively detect low-concentration metabolites in the brain. By developing new techniques that allow for the simultaneous measurement of multiple metabolites across different brain regions, the research aims to enhance the clinical applicability of MRS. The project will utilize innovative methods such as the HERMES and HERCULES approaches to achieve this goal, potentially providing a more comprehensive understanding of brain chemistry. Patients may benefit from these advancements through better diagnosis and monitoring of neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation would include individuals with neurological disorders or conditions that affect brain metabolism.
Not a fit: Patients with conditions unrelated to brain metabolism or those who do not require metabolic monitoring may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic capabilities for various neurological disorders by providing detailed insights into brain metabolite levels.
How similar studies have performed: Previous research has shown promise in using advanced MRS techniques for metabolic analysis, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Barker, Peter B — Johns Hopkins University
- Study coordinator: Barker, Peter B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.