Detecting liver cancer in HIV patients using immune profiling
Immune profiling to detect viral hepatitis-related liver cancer in HIV-infected patients
This study is looking at how certain immune markers in the blood can help find liver cancer earlier in people who have HIV and hepatitis B or C, aiming to create a better screening method than the usual ultrasound.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10703227 on NIH RePORTER |
What this research studies
This research investigates how immune profiling can be used to detect liver cancer, specifically hepatocellular carcinoma (HCC), in patients who are infected with HIV and also have hepatitis B or C. The study aims to identify immune-related blood biomarkers that can predict the development of HCC, potentially offering a more reliable screening method than current ultrasound techniques. By analyzing blood samples, researchers hope to establish a non-visual approach that could improve early detection of liver cancer in this high-risk population.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-positive individuals who are also co-infected with hepatitis B or C and are at risk for developing liver cancer.
Not a fit: Patients who are HIV-negative or do not have hepatitis B or C may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of liver cancer in HIV-infected patients, improving treatment outcomes.
How similar studies have performed: Previous studies have shown promise in using immune markers for cancer detection, suggesting that this approach could be effective.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Debes, Jose Daniel — University of Minnesota
- Study coordinator: Debes, Jose Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.