Detecting kidney cancer recurrence after treatment
Official title: Multi-modality detection of RCC Recurrence Post Ablation
Funded at Thomas Jefferson University · NIH-10993181 · Data updated 2026-11-12
This study is looking at how well a special type of ultrasound can help find kidney cancer returning after treatment, and it's for patients who have had early-stage kidney cancer and want a safer imaging option.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $589,728 |
| NIH project number | 5R01CA269750-03 |
| Project ID | NIH-10993181 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with early-stage renal cell carcinoma who have undergone localized ablation treatment.
✕Less likely to help
Patients with advanced renal cell carcinoma or those who have not undergone ablation treatment may not benefit from this research.
What this research studies
This research focuses on improving the detection of kidney cancer recurrence following localized ablation, a treatment for early-stage renal cell carcinoma. It aims to evaluate the effectiveness of contrast-enhanced ultrasound (CEUS) compared to traditional imaging methods like contrast-enhanced computed tomography (CECT) and magnetic resonance imaging (CEMRI). The study will involve monitoring patients post-ablation to assess the sensitivity and specificity of CEUS in identifying any signs of cancer recurrence. By utilizing CEUS, the research seeks to provide a safer and more accurate imaging alternative for patients who may have contraindications to other imaging modalities.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and safer methods for monitoring kidney cancer recurrence, improving patient outcomes.
How similar studies have gone: Previous pilot studies have shown promising results for using contrast-enhanced ultrasound in monitoring kidney cancer recurrence, indicating potential for success in this approach.
Where this research is happening
-
Thomas Jefferson University
Philadelphia, United States Active
Researchers
- Principal investigator: Eisenbrey, John — Thomas Jefferson University
- Study coordinator: Eisenbrey, John
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.