Detecting kidney cancer recurrence after treatment

Multi-modality detection of RCC Recurrence Post Ablation

NIH-funded research Thomas Jefferson University · NIH-10993181

This study is looking at how well a special type of ultrasound can help find kidney cancer returning after treatment, and it's for patients who have had early-stage kidney cancer and want a safer imaging option.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionThomas Jefferson University NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10993181 on NIH RePORTER

What this research studies

This research focuses on improving the detection of kidney cancer recurrence following localized ablation, a treatment for early-stage renal cell carcinoma. It aims to evaluate the effectiveness of contrast-enhanced ultrasound (CEUS) compared to traditional imaging methods like contrast-enhanced computed tomography (CECT) and magnetic resonance imaging (CEMRI). The study will involve monitoring patients post-ablation to assess the sensitivity and specificity of CEUS in identifying any signs of cancer recurrence. By utilizing CEUS, the research seeks to provide a safer and more accurate imaging alternative for patients who may have contraindications to other imaging modalities.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with early-stage renal cell carcinoma who have undergone localized ablation treatment.

Not a fit: Patients with advanced renal cell carcinoma or those who have not undergone ablation treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and safer methods for monitoring kidney cancer recurrence, improving patient outcomes.

How similar studies have performed: Previous pilot studies have shown promising results for using contrast-enhanced ultrasound in monitoring kidney cancer recurrence, indicating potential for success in this approach.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.