NIH-funded research NIH-funded research

Detecting HPV mRNA to assess cervical cancer risk in low-resource areas

Official title: Human papillomavirus mRNA detection for assessing cervical cancer risk in resource-limited settings

Funded at Rice University · NIH-10990166 · Data updated 2026-11-12

This study is working on a new, easy, and affordable test to quickly detect high-risk HPV, which can lead to cervical cancer, especially in places that don’t have access to regular screenings, so that women can get the help they need sooner.

More Cervical Cancer research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRice University
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$50,474
NIH project number1F99CA294262-01
Project IDNIH-10990166 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women in low-resource settings who are at risk for cervical cancer due to hrHPV.

Less likely to help

Patients who are not at risk for cervical cancer or those in high-resource settings may not benefit from this research.

What this research studies

This research focuses on developing a new method for detecting high-risk human papillomavirus (hrHPV) mRNA, which is linked to cervical cancer risk. The approach aims to create a simple, cost-effective test that can be used in resource-limited settings where traditional screening methods are not available. By using both provider and self-collected cervical samples, the test will amplify hrHPV mRNA and provide real-time results with minimal user steps. This innovative method seeks to improve early detection and treatment of cervical cancer in underserved populations.

Why it matters

Potential benefit: If successful, this research could lead to more accurate cervical cancer screenings, reducing incidence and mortality rates in low-resource settings.

How similar studies have gone: Previous research has shown that detecting hrHPV mRNA can be a more specific biomarker for cervical cancer risk, indicating potential success for this novel approach.

Where this research is happening

  • Rice University
    Houston, United States
    Active

Researchers

  • Principal investigator: Novak, Emilie Newsham — Rice University
  • Study coordinator: Novak, Emilie Newsham

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.