Detecting gestational diabetes early in pregnancy
Official title: Early Detection of Gestational Diabetes Mellitus in Pregnancy
Funded at Univ of Massachusetts Med Sch Worcester · NIH-10808401 · Data updated 2026-11-12
This study is looking to find better ways to spot gestational diabetes early in pregnancy by using a new screening method that combines health history and easy blood tests, and it's designed for pregnant women who are at higher risk for this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project start | July 10, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $163,039 |
| NIH project number | 1K23HD111526-01A1 |
| Project ID | NIH-10808401 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are high-risk pregnant women in their first trimester.
✕Less likely to help
Patients who are not pregnant or those who do not meet the high-risk criteria for gestational diabetes may not benefit from this research.
What this research studies
This research focuses on improving the early detection of gestational diabetes mellitus (GDM) during the first trimester of pregnancy. It aims to develop a new screening protocol that combines clinical risk factors with simple blood tests to identify women at high risk for GDM. By conducting a pilot randomized controlled trial with 80 high-risk pregnant women, the study will compare early screening methods to standard care practices. The goal is to implement a more effective approach that allows for timely interventions to benefit both mothers and their babies.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and management of gestational diabetes, reducing risks for mothers and their children.
How similar studies have gone: Previous research has shown promise in using early screening methods for gestational diabetes, but this specific approach is novel and aims for clinical implementation.
Where this research is happening
-
Univ of Massachusetts Med Sch Worcester
Worcester, United States Active
Researchers
- Principal investigator: Wilkie, Gianna Lusiye — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Wilkie, Gianna Lusiye
Related research
Other NIH-funded projects on the same topics.
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In Vivo Look at Placental Blood Flow in Gestational Diabetes
A non-invasive MRI study in pregnant people with gestational diabetes and those without will map how placental blood vessels work and relate to baby outcomes.
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Decoding how gestational diabetes links to future coronary artery disease
A study using health records and big data to understand why women who had gestational diabetes later face heart disease, with the goal of guiding prevention.
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Understanding how gestational diabetes and depression during pregnancy affect mothers and their children
This project explores how gestational diabetes and depression during pregnancy might influence a mother's mental health after birth and her child's brain development.
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Better Blood Sugar Goals for Pregnant Women with Gestational Diabetes Who Are Overweight or Obese
This project looks at whether stricter blood sugar goals can help pregnant women who have gestational diabetes and are also overweight or obese have healthier pregnancies and babies.
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Understanding how gestational diabetes develops during pregnancy
This study is looking at how the body's insulin-producing cells change in pregnant women to better understand gestational diabetes and help improve diabetes care for moms both during and after pregnancy.
-
The effects of gestational diabetes and maternal depression on child development
This study looks at how having gestational diabetes and feeling depressed during pregnancy might affect how children develop, and it’s for moms-to-be who want to understand how their health can impact their little ones.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.