Detecting early signs of learning difficulties in Alzheimer's disease

Ahead of the Curve: Early detection and monitoring of learning decrements in Alzheimers disease

NIH-funded research Brigham and Women's Hospital · NIH-11125838

This study is looking for ways to spot early signs of Alzheimer's disease by using online memory and speed tests that you can take for just 10 minutes a day over a week, helping to track any small changes in your thinking skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11125838 on NIH RePORTER

What this research studies

This research focuses on the early detection and monitoring of cognitive changes associated with Alzheimer's disease. It aims to improve current methods by utilizing web-based cognitive testing, which allows for more frequent and scalable assessments of learning abilities. Participants will engage in a Multi-Day Learning Curve (MDLC) assessment, where they will complete memory and processing speed tests for 10 minutes each day over a week. This approach seeks to identify subtle cognitive declines that may indicate the onset of Alzheimer's disease at its preclinical stage.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are at risk for Alzheimer's disease, particularly those experiencing early cognitive changes.

Not a fit: Patients with advanced Alzheimer's disease or those without any cognitive concerns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification of individuals at risk for Alzheimer's disease, allowing for timely interventions and better management of the condition.

How similar studies have performed: Other research has shown promise in using web-based cognitive assessments for early detection of cognitive decline, indicating that this approach could be effective.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.