Detecting early memory decline in older adults at risk for Alzheimer's disease

Early detection & monitoring of memory decline in a representative sample of older adults at risk for Alzheimer's disease and related dementias

NIH-funded research Brigham and Women's Hospital · NIH-10952035

This study is looking for early signs of memory problems in older adults who might be at risk for Alzheimer's disease, using fun digital tools to help track how well they learn and remember things over a week.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10952035 on NIH RePORTER

What this research studies

This research focuses on identifying early signs of memory decline in older adults who are at risk for Alzheimer's disease and related dementias. It utilizes innovative digital tools to track cognitive changes over time, specifically looking at how well individuals can learn and recall information. By testing participants daily over a week, researchers aim to uncover subtle memory failures that may indicate the onset of Alzheimer's pathology. The study seeks to validate these methods in a diverse group of older adults to ensure the findings are applicable to various populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who are at risk for Alzheimer's disease, including those with a family history of cognitive decline or other risk factors.

Not a fit: Patients who are not at risk for Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection of Alzheimer's disease, allowing for timely interventions that may slow cognitive decline.

How similar studies have performed: Previous research has shown promise in using digital tools for cognitive assessment, indicating that this approach could be effective in detecting early memory decline.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.