Detecting colorectal cancer early using advanced imaging techniques
Early detection of colorectal cancer in the traditional and serrated pathways
This study is working on a new way to help doctors find early signs of colorectal cancer more easily during colonoscopies by using special imaging techniques that highlight problem areas, making it better for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10904018 on NIH RePORTER |
What this research studies
This research focuses on improving the early detection of colorectal cancer (CRC) by developing new imaging biomarkers that target specific pathways associated with the disease. The project aims to enhance conventional colonoscopy methods, which often miss subtle pre-malignant lesions. By optimizing peptide monomers that bind to overexpressed proteins in these lesions, the researchers will create a novel imaging strategy using near-infrared fluorescence. This approach will be validated through laboratory tests and will involve the development of a specialized endoscopic accessory for in vivo imaging.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at high risk for colorectal cancer, such as those with a family history of the disease or previous polyps.
Not a fit: Patients who have already been diagnosed with advanced colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and earlier detection of colorectal cancer, potentially saving lives through timely intervention.
How similar studies have performed: Previous research has shown promise in using targeted imaging techniques for cancer detection, suggesting that this approach could be effective.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Wang, Thomas D — University of Michigan at Ann Arbor
- Study coordinator: Wang, Thomas D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.