Detecting cancers earlier using non-blood samples
Multi-analyte Approach for Earlier Detection of Cancers in Non Plasma Biofluids
This study is looking for new ways to find brain and head and neck cancers early by testing non-invasive samples like saliva and cerebrospinal fluid, which could help doctors catch these cancers sooner and improve treatment outcomes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10930946 on NIH RePORTER |
What this research studies
This research focuses on developing new methods for the early detection of cancers, particularly brain and head and neck cancers, using non-invasive biofluids like cerebrospinal fluid and saliva. The team aims to identify specific DNA markers released by cancer cells in these fluids, which could provide a more effective way to detect these cancers compared to traditional blood tests. By utilizing advanced techniques to analyze these biofluids, the research seeks to create reliable assays that can be used in clinical settings. The goal is to improve early detection, which is crucial for better treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at high risk for brain or head and neck cancers, or those experiencing symptoms related to these conditions.
Not a fit: Patients with cancers that are not detectable through cerebrospinal fluid or saliva may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate cancer detection, potentially improving survival rates for patients.
How similar studies have performed: Previous research has shown promise in using non-blood biofluids for cancer detection, indicating that this approach could be a significant advancement in the field.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Papadopoulos, Nickolas — Johns Hopkins University
- Study coordinator: Papadopoulos, Nickolas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.