Detecting cancer biomarkers using advanced technology
Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers
['FUNDING_OTHER'] · VIRGINIA COMMONWEALTH UNIVERSITY · NIH-11061256
This study is working on a new tool that can quickly and accurately find cancer-related markers in your blood, helping doctors diagnose cancer more reliably and faster than current methods.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VIRGINIA COMMONWEALTH UNIVERSITY (nih funded) |
| Locations | 1 site (RICHMOND, UNITED STATES) |
| Trial ID | NIH-11061256 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new technology platform that allows for the rapid and accurate detection of microRNA (miRNA) cancer biomarkers in patient samples. By utilizing a unique fluorescence resonance energy transfer (FRET)-based sensor, the study aims to achieve high-confidence results in under an hour, addressing the inconsistencies found in current miRNA analysis methods. The approach involves analyzing cell-free circulating miRNAs, which are stable and relevant to cancer diagnosis, to improve the reliability of cancer biomarker detection. This could lead to better diagnostic tools for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals undergoing evaluation for cancer who have detectable levels of miRNA biomarkers.
Not a fit: Patients who do not have cancer or do not have detectable miRNA biomarkers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with more accurate and timely cancer diagnoses through improved biomarker detection.
How similar studies have performed: Other research has shown promise in using advanced detection methods for cancer biomarkers, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
RICHMOND, UNITED STATES
- VIRGINIA COMMONWEALTH UNIVERSITY — RICHMOND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DHAKAL, SOMA — VIRGINIA COMMONWEALTH UNIVERSITY
- Study coordinator: DHAKAL, SOMA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer therapy