Detecting botulinum toxins in animal products and feed.
Official title: Validation of Endopep-MS for qualitative detection of BoNT/A, /C, /CD, /D, and /DC in animal specimens and feed.
Funded at University of California at Davis · NIH-11075633 · Data updated 2026-11-12
This study is working on a new way to quickly and accurately find harmful botulinum toxins in animal samples and feed, which is important for keeping both animals and people safe from botulism.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $49,689 |
| NIH project number | 1U18FD008342-01 |
| Project ID | NIH-11075633 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include veterinarians, farmers, and animal health professionals involved in livestock management and food safety.
✕Less likely to help
Patients who are not involved in animal agriculture or do not work with livestock may not receive direct benefits from this research.
What this research studies
This research focuses on developing a reliable method to detect botulinum toxins (BoNTs) in animal specimens and feed, which is crucial for preventing botulism outbreaks that can affect both animals and humans. The Endopep-MS method, previously used for human botulism detection, will be validated for animal use. The study aims to ensure that veterinary diagnostic laboratories can accurately identify these toxins, thereby enhancing food safety and animal health. By comparing this new method to existing standards, the research seeks to establish a robust protocol for toxin detection.
Why it matters
Potential benefit: If successful, this research could significantly improve the detection of botulinum toxins, enhancing food safety and reducing the risk of botulism outbreaks in both animals and humans.
How similar studies have gone: Previous research has successfully validated the Endopep-MS method for human botulism detection, indicating potential for success in animal applications.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Poppenga, Robert Howard — University of California at Davis
- Study coordinator: Poppenga, Robert Howard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.