Detecting and monitoring fluid buildup in the inner ear
Using a Joint-Otoacoustic Emission Profile to Detect and Monitor Endolymphatic Hydrops in Humans and to Explore Mechanisms of Pathology
This study is looking at how sounds from your inner ear can help spot and track fluid buildup in people with Ménière’s Disease, which could help catch problems early and protect your hearing.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10873800 on NIH RePORTER |
What this research studies
This research focuses on endolymphatic hydrops, a condition associated with Ménière’s Disease, which involves an imbalance of fluid in the inner ear. The study aims to utilize otoacoustic emissions (OAEs), which are sounds produced by the inner ear, to detect and monitor changes in cochlear function related to this condition. By measuring these emissions, researchers hope to identify the presence of fluid buildup early and track its progression over time, potentially preventing further hearing loss. The approach is noninvasive and aims to improve diagnostic accuracy for patients experiencing auditory symptoms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing symptoms of Ménière’s Disease or other cochlear dysfunctions.
Not a fit: Patients without symptoms of cochlear diseases or those who do not have a diagnosis of Ménière’s Disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of hearing loss associated with endolymphatic hydrops.
How similar studies have performed: Previous research has shown that using otoacoustic emissions can effectively monitor cochlear function, indicating potential success for this approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Stiepan, Samantha Marie — University of Southern California
- Study coordinator: Stiepan, Samantha Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.