Designing new vaccines for influenza viruses
Official title: Project 3: Influenza Virus HA and NA Immunogen Design
Funded at Boston Children's Hospital · NIH-11290943 · Data updated 2026-11-12
This study is working on new ways to make flu vaccines stronger so that they can better protect people from getting sick with the flu.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $400,000 |
| NIH project number | 5P01AI089618-13 |
| Project ID | NIH-11290943 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are at higher risk for influenza, such as young children, the elderly, and those with compromised immune systems.
✕Less likely to help
Patients who are not at risk for influenza or those who have already received effective vaccination may not benefit from this research.
What this research studies
This research focuses on creating innovative immunogens that can enhance the immune response against influenza viruses. By designing specific components of the virus, the team aims to improve vaccine effectiveness and provide better protection for individuals. The approach involves advanced techniques in immunology and virology to identify and develop these immunogens. Patients may benefit from more effective vaccines that could lead to fewer cases of influenza and its complications.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines, reducing the incidence and severity of the disease.
How similar studies have gone: Other research has shown promise in developing innovative vaccine strategies for influenza, indicating that this approach has potential for success.
Where this research is happening
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Boston Children's Hospital
Boston, United States Active
Researchers
- Principal investigator: Schmidt, Aaron Gregory — Boston Children's Hospital
- Study coordinator: Schmidt, Aaron Gregory
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.