Depression care and HIV medication support in South African clinics
Implementing depression and adherence treatment in S. Africa HIV care
This project brings a proven counseling program that treats depression and helps people stick to HIV medicines to clinics serving people with HIV in South Africa.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami Coral Gables NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11180494 on NIH RePORTER |
What this research studies
If you join, clinic staff will deliver cognitive behavioral therapy for adherence and depression (CBT-AD) led by nurses as part of routine HIV care. Ten clinics are randomized to receive either a core set or an enhanced set of strategies to help staff adopt and keep using the program. Researchers will track how many patients are reached, changes in depression and medication-taking, and viral suppression over time. The work builds on earlier trials and was designed with community input to fit local clinic realities.
Who could benefit from this research
Good fit: Adults living with HIV who have symptoms of depression and who receive care at the participating South African clinics are the ideal candidates.
Not a fit: People without depression, those not taking antiretroviral therapy, or anyone receiving care outside the participating clinics are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, more people with HIV could get mental health care that improves mood, helps them stay on HIV treatment, and increases viral suppression rates.
How similar studies have performed: Prior trials of CBT-AD have reduced depression and improved antiretroviral adherence, including cost-effective results in South Africa, so this work builds on successful approaches.
Where this research is happening
Coral Gables, United States
- University of Miami Coral Gables — Coral Gables, United States (Active)
Researchers
- Principal investigator: Safren, Steven a — University of Miami Coral Gables
- Study coordinator: Safren, Steven a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.