Dementia partnership improving understanding of Alzheimer's and frontotemporal dementia in Latino communities
Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat2)
This project gathers medical records, brain scans, and genetic information from Latino people with Alzheimer's, frontotemporal dementia, and without dementia to build better models for diagnosis and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11470998 on NIH RePORTER |
What this research studies
If I join, clinicians will collect my health history, cognitive test results, brain imaging, and DNA and compare them with thousands of other Latino and U.S. participants. The team will enroll 3,000 new participants (750 with Alzheimer's, 750 with frontotemporal lobar degeneration, and 1,500 controls) and combine these data with prior ReDLat datasets and related studies. Researchers will study how genetics, brain changes, and social and economic factors interact to shape dementia signs and progression in Latino populations. The work aims to create tools and knowledge that reflect Latino diversity so diagnosis and care can be more accurate and equitable.
Who could benefit from this research
Good fit: Ideal participants are Latino adults diagnosed with Alzheimer's disease or frontotemporal lobar degeneration, as well as Latino adults without cognitive impairment who can provide clinical data, imaging, and DNA samples.
Not a fit: People who are not of Latino ancestry or who are unwilling to provide imaging or genetic samples are unlikely to be recruited or directly helped by this consortium's findings.
Why it matters
Potential benefit: If successful, this work could lead to more accurate, culturally and genetically appropriate diagnosis and care for Latino people with Alzheimer's and frontotemporal dementia.
How similar studies have performed: Earlier ReDLat efforts and related consortium studies demonstrated feasibility and useful datasets, and this project substantially scales up those efforts across more countries and participants.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Miller, Bruce L — University of California, San Francisco
- Study coordinator: Miller, Bruce L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.