Dementia in Latino communities across Latin America and the U.S.
Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat2)
The project gathers health, brain imaging, and genetic information from Latino people to better understand Alzheimer's disease and frontotemporal dementia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11471027 on NIH RePORTER |
What this research studies
If you join, the project will enroll 3,000 new participants across Argentina, Brazil, Chile, Colombia, Mexico, and Peru—750 people with Alzheimer's, 750 with frontotemporal dementia, and 1,500 without dementia—and combine your results with existing ReDLat data. You may be asked to complete clinical and memory tests, have brain scans, and give a blood sample for genetic testing including whole genome sequencing. Researchers will also collect information about education, income, and neighborhood to see how social and economic factors relate to symptoms and brain changes. By bringing together data from Latin America and the U.S., the team hopes to create tools that are more accurate and relevant for Latino patients.
Who could benefit from this research
Good fit: Ideal candidates are Latino adults from the participating countries or U.S. Latino communities who have Alzheimer’s disease or frontotemporal dementia, or Latino adults without dementia willing to undergo testing and give biological samples.
Not a fit: People who are not Latino, who cannot travel to participating sites, or who are unwilling to undergo scans or provide blood samples are unlikely to benefit from direct participation.
Why it matters
Potential benefit: This work could lead to more accurate diagnosis, better risk prediction, and care approaches tailored to Latino populations.
How similar studies have performed: This project builds on prior ReDLat work and related R01 efforts that have successfully collected multimodal data in Latino cohorts, but combining large-scale genetics and imaging across multiple countries at this scale is relatively new.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Miller, Bruce L — University of California, San Francisco
- Study coordinator: Miller, Bruce L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.