Delaware Comprehensive Sickle Cell Center
Official title: The Delaware Comprehensive Sickle Cell Research Center
Funded at Nemours Children's Hospital, Delaware · NIH-11179262 · Data updated 2026-11-12
This program brings together doctors and researchers to create new treatments, tests, and supports for children and adults living with sickle cell disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nemours Children's Hospital, Delaware NIH-funded |
| Lab location | 1 site (Wilmington, United States) |
| Project start | August 1, 2014 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $2,128,939 |
| NIH project number | 5P20GM109021-10 |
| Project ID | NIH-11179262 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adults living with sickle cell disease who can attend participating clinics in Delaware and who are willing to join clinical or biospecimen studies would be ideal candidates.
✕Less likely to help
People without sickle cell disease or those unable to access participating sites in Delaware are unlikely to benefit directly from this center's activities.
What this research studies
You would be part of a coordinated effort based at NEMOURS and partner sites in Delaware that builds on earlier work to grow local sickle cell research and care. The center funds pilot projects, trains investigators, and runs a Clinical Research and Data Informatics Core to collect patient information and biological samples. Specific projects include studying biomarkers linked to severe sickle cell complications, testing targeted interventions, and developing tools to help patients and health care providers manage the disease. Patient engagement is a core activity, so the center will invite people with sickle cell disease to join studies, provide samples, and help shape care-improvement efforts.
Why it matters
Potential benefit: Could lead to better ways to detect and prevent severe complications, improved treatments, and stronger support for patients and clinicians.
How similar studies have gone: Phase 1 of this COBRE helped attract significant funding and early projects, and related translational efforts in sickle cell disease have produced useful biomarkers and care improvements, although some interventions remain novel and unproven.
Where this research is happening
-
Nemours Children's Hospital, Delaware
Wilmington, United States Active
Researchers
- Principal investigator: Brousseau, David C — Nemours Children's Hospital, Delaware
- Study coordinator: Brousseau, David C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.