Deciding together about Alzheimer’s treatment options
Helping Patients, Families, and Clinicians Make Shared Decisions about Therapies for Dementia
['FUNDING_R21'] · UNIVERSITY OF COLORADO DENVER · NIH-11187242
This project will create a clear decision guide to help people with Alzheimer’s, their families, and clinicians talk through the benefits and risks of new anti-amyloid treatments.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11187242 on ClinicalTrials.gov |
What this research studies
If you or a family member are facing choices about Alzheimer’s drugs like lecanemab, this project will gather input from patients, caregivers, and clinicians to learn what information matters most to you. The team will use that feedback in repeated design cycles to build a patient decision aid that explains likely benefits, risks, and practical issues in everyday language. They will test the tool with people affected by dementia and refine it based on real user experience. The goal is a usable guide clinicians can use during appointments to support shared decision making.
Who could benefit from this research
Good fit: Ideal candidates include people diagnosed with Alzheimer’s disease or their caregivers who are considering or discussing anti-amyloid treatments with clinicians.
Not a fit: People without cognitive disorders or those not facing a decision about Alzheimer’s treatments are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, the decision aid could help patients and families make more informed, confident choices about anti-amyloid therapies and other dementia care options.
How similar studies have performed: Patient decision aids have improved decision quality in other medical areas, but applying them specifically to dementia care and the new amyloid drugs is relatively new.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MATLOCK, DANIEL D — UNIVERSITY OF COLORADO DENVER
- Study coordinator: MATLOCK, DANIEL D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease