Data tools to spot health risks and guide care for children with HIV
DSpace: Utilizing Data Science to Predict and Improve Health Outcomes in Pediatric HIV
['FUNDING_U01'] · UNIVERSITY OF BOTSWANA · NIH-11168815
This project uses data and AI to spot which children and teens with HIV are more likely to develop metabolic problems or tuberculosis so care can be improved.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF BOTSWANA (nih funded) |
| Locations | 1 site (GABORONE, BOTSWANA) |
| Trial ID | NIH-11168815 on ClinicalTrials.gov |
What this research studies
If my child joins, researchers will collect clinical information like symptoms, lab tests, treatment history, and any available samples from children and teens with HIV and use computer models to find patterns linked to metabolic syndrome and TB. They will adapt data-science tools that have been used in adults to local pediatric data from Botswana and other sites in sub-Saharan Africa, then test how well those tools identify disease and risk. The team will compare model findings with clinic follow-up and diagnostic information to confirm results. The goal is to create practical tools doctors can use locally to spot problems earlier and personalize care for children with HIV.
Who could benefit from this research
Good fit: Children and adolescents living with HIV (roughly newborns through young adults under 21) receiving care at participating clinics in Botswana or similar sub-Saharan African settings would be the ideal candidates.
Not a fit: People without HIV, adults outside the study age range, or patients not seen at participating clinics are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, the work could help clinicians detect tuberculosis and metabolic complications earlier in children with HIV and reduce illness and deaths.
How similar studies have performed: Related AI and data-driven approaches have shown promise for TB and metabolic risk in adult Western populations, but they have not been widely tested or validated in African children, making this adaptation and local testing novel.
Where this research is happening
GABORONE, BOTSWANA
- UNIVERSITY OF BOTSWANA — GABORONE, BOTSWANA (ACTIVE)
Researchers
- Principal investigator: RETSHABILE, GAONE — UNIVERSITY OF BOTSWANA
- Study coordinator: RETSHABILE, GAONE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus