NIH-funded research U01 cooperative agreement

Data tools to find health risks in children and teens living with HIV

Official title: DSpace: Utilizing Data Science to Predict and Improve Health Outcomes in Pediatric HIV

Funded at University of Botswana · NIH-11383289 · Data updated 2026-11-12

This project uses computer-based data tools to spot risks like metabolic problems and hidden tuberculosis in children and adolescents with HIV in Botswana and similar settings.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Botswana
NIH-funded
Lab location1 site (Gaborone, Botswana)
Project startSeptember 18, 2023
Project endAugust 31, 2026
Funding year2025
Award (this year)$65,703
NIH project number3U01HD114479-03S1
Project IDNIH-11383289 on NIH RePORTER

Who could benefit from this research

Could help

Children and adolescents living with HIV who receive care at participating clinics in Botswana (roughly ages 0–20) and whose caregivers agree to share medical records and samples are ideal candidates.

Less likely to help

People without HIV, adults older than the study age range, or those not receiving care at participating sites are unlikely to benefit directly from this project.

What this research studies

You or your child may be asked to let doctors use clinic records, lab results, and sometimes blood samples to teach computer programs to recognize who is at risk for metabolic syndrome or undetected TB. The team will adapt tools that worked in adults and try them with children and teens in Botswana to see how well they identify real health problems. Participation could include extra screenings or sharing existing medical information from clinic visits. The goal is to help clinicians find and treat problems earlier for better long-term health.

Why it matters

Potential benefit: If successful, these tools could help catch metabolic problems and hidden TB earlier in children with HIV so they receive treatment sooner and avoid long-term complications.

How similar studies have gone: Related computer-based risk tools have shown promise in adult populations in Western countries, but applying them to children with HIV in Africa is relatively new and untested.

Where this research is happening

  • University of Botswana
    Gaborone, Botswana
    Active

Researchers

  • Principal investigator: Retshabile, Gaone — University of Botswana
  • Study coordinator: Retshabile, Gaone

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.