Data hub for genes linked to healthy aging and longevity
Data Integration and Sharing Core
This project combines genetic and health data from long-lived centenarians and typical adults to find genes that help people stay healthier as they age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11161514 on NIH RePORTER |
What this research studies
If you take part, researchers will combine genetic and medical information from very old healthy people and comparison volunteers to look for rare protective gene variants. A centralized Data Integration and Sharing Core will clean, harmonize, and analyze large datasets across multiple linked projects so findings can be compared and shared. The team will search for genetic changes that seem to protect against diabetes, cancer, and heart disease and point to possible drug targets. Your samples or data could help researchers discover ways to delay or prevent multiple age-related illnesses.
Who could benefit from this research
Good fit: Ideal candidates include very old healthy individuals (centenarians) and adult volunteers willing to share genetic and medical information as comparison controls.
Not a fit: People who are not willing or able to provide genetic or medical data, or those seeking immediate treatment benefits, are unlikely to gain direct clinical benefit from participation.
Why it matters
Potential benefit: This work could identify genes and drug targets that help prevent or delay diabetes, cancer, and cardiovascular disease and extend healthy lifespan.
How similar studies have performed: Previous centenarian genetics studies have found promising protective variants, but combining multiple projects through a dedicated data core to target drug discovery is a newer, more integrated approach.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Zhang, Zhengdong — Albert Einstein College of Medicine
- Study coordinator: Zhang, Zhengdong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.