Data and statistics support for diabetes and Alzheimer's outcomes
Biostatistics and Data Infrastructure core
This project helps researchers analyze long-term diabetes prevention data to learn how diabetes and its treatments relate to Alzheimer's disease and related dementias in older adults.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11367309 on NIH RePORTER |
What this research studies
From a central team at Columbia, statisticians will manage and harmonize data from the Diabetes Prevention Program Outcomes Study to ensure consistent definitions and high-quality datasets. They will plan study designs, calculate sample sizes and statistical power, and run analyses that link diabetes prevention and treatment history to cognitive and brain health outcomes. The Data Core will support other project teams working on cognitive testing, imaging, and biomarkers so their results can be combined and compared. They will also prepare data and analysis plans for publications and for sharing with outside researchers.
Who could benefit from this research
Good fit: People who took part in the Diabetes Prevention Program or its long-term follow-up (DPPOS), especially older adults with past prediabetes or diabetes or concerns about memory, are the participants whose data this project will use.
Not a fit: Individuals who were never part of DPP/DPPOS or who lack follow-up data in that network are unlikely to see direct benefit from this grant's activities.
Why it matters
Potential benefit: If successful, this work could clarify whether preventing or treating diabetes lowers the risk of Alzheimer's and related dementias and inform better prevention strategies.
How similar studies have performed: The original DPP and DPPOS showed clear benefits for diabetes prevention and provide a strong foundation for analyzing links to brain health, but using those data to prove an effect on Alzheimer's remains an active and not-yet-settled research question.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Temprosa, Marinella — Columbia University Health Sciences
- Study coordinator: Temprosa, Marinella
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.