Data and bioinformatics support for cancer care in Hawaiʻi
Core 1: Biostatistics & Bioinformatics Core
This project helps researchers use data and advanced computer methods to improve prevention, screening, and risk prediction for cancers affecting Asian American, Native Hawaiian, and Pacific Islander people in Hawaiʻi.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-11184191 on NIH RePORTER |
What this research studies
As someone living in Hawaiʻi, this effort supports multiple cancer projects by providing study design, data management, and advanced statistical and bioinformatics analysis. The core helps a randomized trial testing intermittent energy restriction to reduce liver fat and stiffness in people with NAFLD, work to improve lung cancer screening and understand smoking-related risks in Native Hawaiians, and projects adding mammography radiomic features to breast cancer risk models for AANHPI women. Staff coordinate data processing, run Bayesian and other statistical methods, and help translate results back to clinical teams. Their work is focused on making the research more accurate and relevant to AANHPI populations in Hawaiʻi.
Who could benefit from this research
Good fit: Ideal candidates are Asian American, Native Hawaiian, or Pacific Islander adults in Hawaiʻi who have or are at risk for liver disease (NAFLD), lung cancer risk (including smokers), or breast cancer screening concerns.
Not a fit: People living outside Hawaiʻi, without liver, lung, or breast cancer concerns, or unwilling to take part in research are less likely to benefit directly.
Why it matters
Potential benefit: If successful, this work could lead to better prevention strategies, more effective screening, and more accurate breast cancer risk predictions for AANHPI communities in Hawaiʻi.
How similar studies have performed: Previous trials of intermittent energy restriction and studies using radiomics or tailored screening have shown promise, but combining these approaches and focusing on AANHPI populations in Hawaiʻi is relatively novel.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Wilkens, Lynne R — University of Hawaii at Manoa
- Study coordinator: Wilkens, Lynne R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.