Data and analytics for oropharyngeal cancer survivorship care
Core B: Clinical Informatics & Analytics
['FUNDING_P01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-11180373
This project builds tools to combine clinical and biomarker data to find non-invasive signs and patterns of late treatment effects in people who survived oropharyngeal (throat) cancer.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11180373 on ClinicalTrials.gov |
What this research studies
Core B will build and manage a centralized data infrastructure and customized informatics pipelines to integrate clinical, imaging, and biomarker data from MD Anderson oropharynx survivor cohorts. The team will apply an oropharynx-specific ontology, implement automated quality-control checks, and create interactive dashboards for researchers to explore patient trajectories and delayed adverse effects. Biostatisticians will provide coordinated analytic support including study design input and Bayesian methods across the program's projects. The deliverables aim to produce clinic-ready, non-invasive markers and sharable data products to help teams develop ways to reduce late treatment harms and improve survivors' quality of life.
Who could benefit from this research
Good fit: Adults who have completed treatment for oropharyngeal cancer and who are enrolled in or eligible for the MD Anderson or affiliated OPC survivor cohorts are the ideal participants for the studies supported by this core.
Not a fit: People without a history of oropharyngeal cancer or those not enrolled in the study cohorts are unlikely to receive direct benefit from this grant's work.
Why it matters
Potential benefit: If successful, this work could help detect early, non-invasive signs of late treatment side effects so doctors can intervene sooner and improve long-term quality of life for oropharyngeal cancer survivors.
How similar studies have performed: Related clinical-informatics and biomarker projects in cancer survivorship have identified patterns of late effects, but this integrated, OPC-specific informatics pipeline is a newer and more tailored approach.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MORENO, AMY CATHERINE — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: MORENO, AMY CATHERINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.