NIH-funded research R01 grant

Daily experiences and cognitive drivers of weight loss success in adults with obesity

Official title: Daily experiences and cognitive mediators of behavioral obesity treatment outcomes

Funded at Rush University Medical Center · NIH-11402698 · Data updated 2026-11-12

This study looks at why some adults with obesity have better weight loss results than others when following a standard weight loss program.

More Obesity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRush University Medical Center
NIH-funded
Lab location1 site (Chicago, United States)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$649,486
NIH project number5R01HL156622-05
Project IDNIH-11402698 on NIH RePORTER

Who could benefit from this research

Could help

Adults with obesity who are starting or currently undergoing a standard weight loss program and are able to participate in follow-up assessments.

Less likely to help

Patients not following the weight loss program as planned or unable to complete follow-up assessments may not benefit.

What this research studies

Researchers will enroll adults with obesity in a standard weight loss program and track their weight loss, adherence to diet and activity, and daily experiences over six months. They will measure cognitive factors like present bias and how stress or daily challenges affect eating and self-control. The goal is to identify behavioral and cognitive patterns that predict who does well and why, so future programs can be tailored to individual needs. Participants will complete assessments and provide information on their diet, activity, and daily experiences during follow-up visits.

Why it matters

Potential benefit: If successful, findings could help personalize obesity treatments to improve weight loss outcomes for more patients.

How similar studies have gone: Prior research has linked cognitive factors and daily experiences to weight loss patterns, with potential to improve personalized interventions.

Where this research is happening

  • Rush University Medical Center
    Chicago, United States
    Active

Researchers

  • Principal investigator: Appelhans, Bradley M. — Rush University Medical Center
  • Study coordinator: Appelhans, Bradley M.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.