Daily experiences and cognitive drivers of weight loss success in adults with obesity
Official title: Daily experiences and cognitive mediators of behavioral obesity treatment outcomes
Funded at Rush University Medical Center · NIH-11402698 · Data updated 2026-11-12
This study looks at why some adults with obesity have better weight loss results than others when following a standard weight loss program.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $649,486 |
| NIH project number | 5R01HL156622-05 |
| Project ID | NIH-11402698 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with obesity who are starting or currently undergoing a standard weight loss program and are able to participate in follow-up assessments.
✕Less likely to help
Patients not following the weight loss program as planned or unable to complete follow-up assessments may not benefit.
What this research studies
Researchers will enroll adults with obesity in a standard weight loss program and track their weight loss, adherence to diet and activity, and daily experiences over six months. They will measure cognitive factors like present bias and how stress or daily challenges affect eating and self-control. The goal is to identify behavioral and cognitive patterns that predict who does well and why, so future programs can be tailored to individual needs. Participants will complete assessments and provide information on their diet, activity, and daily experiences during follow-up visits.
Why it matters
Potential benefit: If successful, findings could help personalize obesity treatments to improve weight loss outcomes for more patients.
How similar studies have gone: Prior research has linked cognitive factors and daily experiences to weight loss patterns, with potential to improve personalized interventions.
Where this research is happening
-
Rush University Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Appelhans, Bradley M. — Rush University Medical Center
- Study coordinator: Appelhans, Bradley M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.