CureGN Penn: a study for people with primary glomerular kidney diseases
CureGN-Penn PCC
This long-term project follows children and adults with certain primary kidney diseases to collect medical data and samples that can help improve care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11381253 on NIH RePORTER |
What this research studies
If you or your child have a primary glomerular disease like MCD, FSGS, IgA nephropathy, or membranous nephropathy, joining means periodic clinic visits, giving blood and urine samples, and sharing health and symptom information. The study follows participants over time and gathers biospecimens, clinical records, and patient-reported outcomes to create a detailed picture of each disease. Researchers from many centers collaborate with patient groups and industry to use these materials for clinical, mechanistic, and translational research. The goal is to speed discoveries that lead to better diagnosis, monitoring, and more targeted treatments.
Who could benefit from this research
Good fit: People (children and adults) diagnosed with primary glomerular diseases—minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy—who can attend a participating clinic are ideal candidates.
Not a fit: People without these primary glomerular diagnoses, those with secondary causes of kidney disease, or those unable to attend follow-up visits are unlikely to gain direct benefit from this study.
Why it matters
Potential benefit: If successful, the study could help doctors identify disease patterns and biomarkers that lead to earlier diagnosis and more effective, personalized treatments.
How similar studies have performed: Other observational kidney registries have helped reveal disease patterns and candidate biomarkers, and CureGN is larger and more deeply phenotyped than most prior efforts.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Holzman, Lawrence B. — University of Pennsylvania
- Study coordinator: Holzman, Lawrence B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.