CureGN network for primary glomerular kidney diseases (MCD, FSGS, IgA nephropathy, membranous nephropathy)
The Columbia PCC for CureGN: the Cure Glomerulonephropathy network
['FUNDING_U01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11381247
People (children and adults) with MCD, FSGS, IgA nephropathy, or membranous nephropathy share health information and biospecimens so researchers can learn how these kidney diseases start, change over time, and respond to treatment.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11381247 on ClinicalTrials.gov |
What this research studies
You would join a large, ongoing network that follows both children and adults with the four main primary glomerular diseases. Clinic teams collect medical records, blood and urine samples, patient surveys, and when available leftover biopsy tissue at regular visits. Data and biospecimens from nearly 2,800 participants are linked across more than 60 clinical sites to enable long-term clinical and lab studies. The network partners with patient groups and multiple medical centers to speed discoveries that may inform better tests and therapies.
Who could benefit from this research
Good fit: Adults and children diagnosed with minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy who receive care at or can travel to a participating site.
Not a fit: People without these specific glomerular diseases or those unable to attend a participating clinic are unlikely to participate or gain direct benefit from this network.
Why it matters
Potential benefit: This work could identify markers and disease patterns that help personalize care and predict who will respond to specific treatments.
How similar studies have performed: Large observational kidney cohorts have previously found useful risk markers and informed trials, and CureGN is one of the largest efforts applying this approach to primary glomerular diseases.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOMBACK, ANDREW STEPHEN — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: BOMBACK, ANDREW STEPHEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.