CureGN network for primary glomerular (kidney) diseases

The Columbia PCC for CureGN: the Cure Glomerulonephropathy network

NIH-funded research Columbia University Health Sciences · NIH-11166636

This project collects medical information and blood/urine samples from children and adults with primary glomerular kidney diseases like minimal change disease, FSGS, IgA nephropathy, and membranous nephropathy.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11166636 on NIH RePORTER

What this research studies

You would join a network that follows people with primary glomerular diseases over time and gathers clinical data, patient-reported outcomes, and biospecimens (blood, urine, tissue when available). The study has enrolled nearly 2,800 adults and children at more than 60 clinical sites and is run by a coordinated Data Coordinating Center and several participating clinical centers. Collected samples and data support a range of research projects on disease causes, how disease progresses, and why people respond differently to treatments. Participation may involve clinic visits, questionnaires, and sample collection at a nearby study site.

Who could benefit from this research

Good fit: People of any age (children and adults) diagnosed with primary glomerular diseases—minimal change disease, focal segmental glomerulosclerosis (FSGS), IgA nephropathy (IgAN), or membranous nephropathy (MN)—are the ideal candidates.

Not a fit: People without these primary glomerular diagnoses, those with kidney disease from other known secondary causes, or those already on long-term dialysis may not directly benefit from this project.

Why it matters

Potential benefit: If successful, this work could help doctors better diagnose causes of glomerular diseases and guide more effective, personalized treatments in the future.

How similar studies have performed: This is an established, large observational network that has already recruited a diverse cohort and supported multiple translational studies rather than being a brand-new, untested approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.