CureGN at UNC: Tracking glomerular kidney diseases in children and adults
CureGN-3: UNCPCC
Following adults and children with specific glomerular kidney diseases over time to collect health information and samples that can help improve care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11381244 on NIH RePORTER |
What this research studies
If you join CureGN at UNC, you would have regular clinic visits where doctors collect medical information, questionnaires about symptoms and quality of life, and biospecimens like blood and urine. The program follows people with minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy over months and years to learn how these conditions change and respond to treatment. Data and samples are combined with those from many other sites to support research on causes, biomarkers, and better therapies. Participation is observational, so you would not be given experimental drugs as part of this protocol, but your information could help shape future trials and care.
Who could benefit from this research
Good fit: Children and adults diagnosed with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), IgA nephropathy (IgAN), or membranous nephropathy (MN) are the primary candidates for participation.
Not a fit: People without these specific glomerular diagnoses or those unwilling to attend follow-up visits or provide biospecimens are unlikely to gain direct benefit from participating.
Why it matters
Potential benefit: This work could lead to better ways to predict disease course and tailor treatments for people with these glomerular diseases.
How similar studies have performed: Large observational kidney disease cohorts have previously improved understanding of disease patterns and outcomes, and CureGN builds on that work with larger numbers and deeper biospecimen collection.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Falk, Ronald J — Univ of North Carolina Chapel Hill
- Study coordinator: Falk, Ronald J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.