CureGN at UNC: improving care for common glomerular kidney diseases
CureGN-3: UNCPCC
['FUNDING_U01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11166601
Collecting medical information and blood, urine, and tissue samples from children and adults with minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy to understand how these diseases progress and respond to treatment.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-11166601 on ClinicalTrials.gov |
What this research studies
This project follows adults and children diagnosed with four primary glomerular diseases over time at many clinical sites, including UNC Chapel Hill. Participants give clinical data, patient-reported outcomes, and biospecimens such as blood, urine, and stored kidney tissue. The research team links these data to treatments and outcomes to find patterns that explain why disease behaves differently between people. The consortium of clinicians, researchers, patients, advocacy groups, and industry partners supports many future analyses and collaborations.
Who could benefit from this research
Good fit: Ideal participants are children or adults diagnosed with minimal change disease, focal segmental glomerulosclerosis, IgA nephropathy, or membranous nephropathy who can attend clinic visits and provide medical records and samples.
Not a fit: People without these specific glomerular diagnoses or those unwilling to share records or provide biospecimens are unlikely to receive direct benefit from participating.
Why it matters
Potential benefit: If successful, this work could help doctors predict disease course, choose better treatments, and speed development of new therapies for glomerular kidney diseases.
How similar studies have performed: This builds on prior large observational kidney cohorts and has already enrolled nearly 2,800 participants, so the approach is well established rather than experimental.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FALK, RONALD J — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: FALK, RONALD J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.