CureGN at Penn: Glomerular Kidney Disease Registry

CureGN-Penn PCC

['FUNDING_U01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11381255

Following children and adults with four types of primary glomerular kidney disease to collect health information and biological samples to improve future care.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11381255 on ClinicalTrials.gov

What this research studies

If I join CureGN at Penn, my doctors will collect my medical records, blood and urine samples, and my own reports about symptoms and quality of life over time. The project follows people with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), IgA nephropathy (IgAN), and membranous nephropathy (MN) at regular visits. Samples and data are stored in a central biobank and database and shared with approved researchers across a collaborative network. The team links clinical events, laboratory findings, and patient-reported outcomes to find patterns that could lead to better diagnosis and treatments.

Who could benefit from this research

Good fit: People of any age diagnosed with MCD, FSGS, IgAN, or MN who receive care at a participating CureGN clinical site are ideal candidates.

Not a fit: People without these specific glomerular diseases or those unable to attend visits at participating centers are unlikely to gain direct benefits from this project.

Why it matters

Potential benefit: Could help doctors understand disease courses and develop better, more personalized treatments for people with these glomerular kidney diseases.

How similar studies have performed: Large kidney disease cohorts have previously improved care and biomarker discovery, and CureGN is a larger, more deeply phenotyped effort building on that success.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.