Culturally tailored smoking-cessation resources for American Indian adults

Randomized Clinical Trial of a Culturally-Tailored Suite of Smoking Cessation Resources for American Indian Persons

NIH-funded research University of Minnesota · NIH-11195603

This project offers culturally adapted text messages, a smartphone app, and online community support to help American Indian adults quit commercial cigarette smoking.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11195603 on NIH RePORTER

What this research studies

You would be offered a suite of culturally aligned digital supports, including Smokefree TXT for Natives, QuitGuide for Natives (smartphone app), and an online community called Quit Connections. The team developed these tools with input from tribes, American Indian-serving clinics, and community advisory boards to respect Indigenous worldviews and traditional uses of tobacco. Participants are randomly assigned to receive the culturally tailored suite or standard resources and will be followed over time to track quitting. The study uses self-report and standard measures of abstinence collected remotely, and may include biochemical confirmation depending on the protocol.

Who could benefit from this research

Good fit: American Indian adults (18+) who currently smoke commercially produced cigarettes, want to try to quit, and can receive text messages or use an Android smartphone app.

Not a fit: People who only use tobacco for traditional or ceremonial purposes, who are not interested in quitting, or who lack access to a mobile phone may not benefit from these digital resources.

Why it matters

Potential benefit: If successful, this could help more American Indian adults quit smoking by providing culturally relevant support that fits community values.

How similar studies have performed: General Smokefree digital programs have improved quit rates in broader populations, and early pilot work with culturally tailored tools for American Indian communities is promising though large randomized results are still limited.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.